Isopropyl myristate is an ester of isopropyl alcohol and myristic acid, commonly used in cosmetic formulations [1]. It functions primarily as an emollient, solvent, and skin conditioning agent. The substance is valued for its ability to impart a non-greasy feel to products, enhancing their texture and spreadability [2].

The production process of isopropyl myristate typically involves an esterification reaction between myristic acid and isopropyl alcohol, often catalyzed by an acid. The reaction is performed under controlled conditions to ensure high yield and purity of the final product. Post-reaction, the mixture undergoes purification processes such as distillation to remove excess reactants and by-products [3].

Isopropyl myristate serves multiple functions in cosmetic formulations. As an emollient, it helps to soften and smooth the skin. It acts as a solvent for hydrophobic ingredients like fragrances and certain active compounds, and also aids in the uniform dispersion of ingredients within a formulation [4]. Furthermore, it assists in skin conditioning by creating a barrier on the skin's surface, which helps to prevent moisture loss [5].

Isopropyl myristate finds use in a wide array of cosmetic and personal care products. These include lotions, creams, sunscreens, makeup, and hair care products [6]. Its versatility makes it a valuable ingredient for enhancing the aesthetic and functional properties of these applications.

Isopropyl myristate is typically packaged in airtight containers to prevent contamination and degradation from exposure to air and moisture. Transportation should adhere to standard practices for chemical substances, ensuring that containers are properly labeled and handled to prevent damage during transit [7].

Citations:
[1] Johnson, W., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Marks, J. G. (2012). Final report on the safety assessment of isopropyl myristate, isopropyl palmitate, myristyl myristate, isopropyl isostearate, and isostearyl isostearate. International journal of toxicology, 31(5_suppl), 77S-112S.
[2] Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., … & Olson, B. J. (1985). Measurement of protein using bicinchoninic acid. Analytical biochemistry, 150(1), 76-85.
[3] O'Lenick, A. J., & O'Lenick Jr, T. G. (2000). Emollients. Allured Pub.
[4] Draelos, Z. D. (2018). Cosmetic dermatology. John Wiley & Sons.
[5] Lodén, M., & Andersson, A. C. (2017). Textbook of cosmetic dermatology. CRC press.
[6] Schnuch, A., Uter, W., Geier, J., Lessmann, H., Frosch, P. J., & Rustemeyer, T. (2007). Sensitization to isopropyl myristate: results of the IVDK data and literature review. Contact dermatitis, 57(1), 1-6.
[7] European Chemicals Agency. (2023). Information on Registered Substances: Isopropyl myristate. https://echa.europa.eu/

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